Activation of a Ca2+-dependent Protein Kinase Involves Intramolecular Binding of a Calmodulin-like Regulatory Domain

Notes on a 1996 Biochemistry paper revealing that activation of CDPK involves intramolecular binding between its calmodulin-like domain (CaM-LD) and junction/autoinhibitor, offering deep insights into Ca2+-regulated protein kinase activation.

Activation of a Ca2+-dependent Protein Kinase Involves Intramolecular Binding of a Calmodulin-like Regulatory Domain

Notes on a 1996 Biochemistry paper revealing that activation of CDPK involves intramolecular binding between its calmodulin-like domain (CaM-LD) and junction/autoinhibitor, offering deep insights into Ca2+-regulated protein kinase activation.

Tobacco Calcium-Dependent Protein Kinases Are Differentially Phosphorylated In Vivo as Part of a Kinase Cascade That Regulates Stress Response

Notes on a 2010 JBC paper investigating in vivo phosphorylation of tobacco CDPKs (NtCDPK2 and NtCDPK3) in response to stress, revealing distinct intra- and inter-molecular phosphorylation events, N-terminal-specific regulation, and the critical role of membrane localization.

Tobacco Calcium-Dependent Protein Kinases Are Differentially Phosphorylated In Vivo as Part of a Kinase Cascade That Regulates Stress Response

Notes on a 2010 JBC paper investigating in vivo phosphorylation of tobacco CDPKs (NtCDPK2 and NtCDPK3) in response to stress, revealing distinct intra- and inter-molecular phosphorylation events, N-terminal-specific regulation, and the critical role of membrane localization.

Autophosphorylation-Dependent Activation of a Calcium-Dependent Protein Kinase from Groundnut

Notes on a 1999 ASPS paper analyzing autophosphorylation-dependent activation of a calcium-dependent protein kinase (GnCDPK) from groundnut and its role in substrate phosphorylation.

Autophosphorylation-Dependent Activation of a Calcium-Dependent Protein Kinase from Groundnut

Notes on a 1999 ASPS paper analyzing autophosphorylation-dependent activation of a calcium-dependent protein kinase (GnCDPK) from groundnut and its role in substrate phosphorylation.

Rapid Whole Cell Imaging Reveals a Calcium-APPL1-Dynein Nexus that Regulates Cohort Trafficking of Stimulated EGF Receptors

Notes on the 2021 Nature Communications paper revealing a calcium-dependent APPL1-dynein mechanism that coordinates collective EGFR trafficking to the perinuclear region following stimulation.

Rapid Whole Cell Imaging Reveals a Calcium-APPL1-Dynein Nexus that Regulates Cohort Trafficking of Stimulated EGF Receptors

Notes on the 2021 Nature Communications paper revealing a calcium-dependent APPL1-dynein mechanism that coordinates collective EGFR trafficking to the perinuclear region following stimulation.

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