Note on the detailed structural study of CDPK activation, focusing on apicomplexan CAD conformations (CpCDPK, PfCDPK3), offering new insight into a potentially universal activation mechanism for CDPKs.
Note on the detailed structural study of CDPK activation, focusing on apicomplexan CAD conformations (CpCDPK, PfCDPK3), offering new insight into a potentially universal activation mechanism for CDPKs.
Notes on a 2023 The Plant Cell study that introduces a genetically encoded FRET-based biosensor to monitor real-time conformational changes of CDPKs (CPKs) in response to calcium signals in vivo, highlighting distinct calcium sensitivities of CPK21 and CPK23 in stress responses.
Notes on a 2023 The Plant Cell study that introduces a genetically encoded FRET-based biosensor to monitor real-time conformational changes of CDPKs (CPKs) in response to calcium signals in vivo, highlighting distinct calcium sensitivities of CPK21 and CPK23 in stress responses.
Notes on a 2004 JBC paper exploring differential roles of N- and C-lobes in the CaM-like domain (CaM-LD) of CDPK, uncovering distinct Ca2+ affinities and their role in regulating kinase activation through interactions with the junction domain.
Notes on a 2004 JBC paper exploring differential roles of N- and C-lobes in the CaM-like domain (CaM-LD) of CDPK, uncovering distinct Ca2+ affinities and their role in regulating kinase activation through interactions with the junction domain.
