Notes on 2008 Biophysical Journal paper analyzing the thermodynamics of membrane insertion for an H-ras lipopeptide anchor (ANCH), highlighting the role of enthalpy-driven hydrophobic effects and conformational selection.
Notes on 2008 Biophysical Journal paper analyzing the thermodynamics of membrane insertion for an H-ras lipopeptide anchor (ANCH), highlighting the role of enthalpy-driven hydrophobic effects and conformational selection.
A deep dive into the molecular dynamics and membrane interaction of EGFR, revealing distinct active and inactive conformations, the role of lipid environment, and subtle structural regulation.
A deep dive into the molecular dynamics and membrane interaction of EGFR, revealing distinct active and inactive conformations, the role of lipid environment, and subtle structural regulation.
An in-depth study of EGFR activation focusing on transmembrane and juxtamembrane coupling, density-dependent activation, and the role of the plasma membrane in maintaining autoinhibition.
An in-depth study of EGFR activation focusing on transmembrane and juxtamembrane coupling, density-dependent activation, and the role of the plasma membrane in maintaining autoinhibition.
Notes on a 2004 Plant Cell paper mapping Arabidopsis plasma membrane phosphoproteins and phosphorylation sites.
Notes on a 2004 Plant Cell paper mapping Arabidopsis plasma membrane phosphoproteins and phosphorylation sites.
Note on the differential calcium sensitivity among Arabidopsis CDPK isoforms, highlighting the diversity of activation mechanisms and implications for calcium signaling in plants.
Note on the differential calcium sensitivity among Arabidopsis CDPK isoforms, highlighting the diversity of activation mechanisms and implications for calcium signaling in plants.
Notes on a landmark 1998 EMBO paper identifying αKAP as the first anchoring protein for CaM kinase II, revealing how αKAP targets CaMKII to the sarcoplasmic reticulum in skeletal muscle and enables tissue-specific membrane localization and signaling control.
Notes on a landmark 1998 EMBO paper identifying αKAP as the first anchoring protein for CaM kinase II, revealing how αKAP targets CaMKII to the sarcoplasmic reticulum in skeletal muscle and enables tissue-specific membrane localization and signaling control.
A comprehensive study unraveling the molecular dynamics of recoverin’s membrane binding via its calcium-dependent myristoyl switch, highlighting the importance of N-terminal domain conformations and transient C-terminal interactions.
A comprehensive study unraveling the molecular dynamics of recoverin’s membrane binding via its calcium-dependent myristoyl switch, highlighting the importance of N-terminal domain conformations and transient C-terminal interactions.
Notes on a 2000 Plant Journal paper identifying dual lipid modifications — myristoylation and palmitoylation — as essential for membrane targeting of rice CDPK (OsCDPK2), marking the first report of such dual acylation in plant CDPKs.
