Regulation of Protein Kinases: Activation Segment Conformation and Functional Control

Notes on 2004 Molecular Cell review analyzing how activation segment conformation regulates protein kinase activity, including insights into RD pocket, anchor residues, and alternative activation mechanisms.

Regulation of Protein Kinases: Activation Segment Conformation and Functional Control

Notes on 2004 Molecular Cell review analyzing how activation segment conformation regulates protein kinase activity, including insights into RD pocket, anchor residues, and alternative activation mechanisms.

Community Analysis of PKA: A Dynamic View of Kinase Architecture

Notes on a 2014 PNAS paper analyzing PKA dynamics through community analysis.

Protein Kinases: Evolution of Dynamic Regulatory Proteins

Notes on 2010 Cell Review article exploring the structural and evolutionary principles that shape the dynamic regulatory mechanisms of protein kinases.

Protein Kinases: Evolution of Dynamic Regulatory Proteins

Notes on 2010 Cell Review article exploring the structural and evolutionary principles that shape the dynamic regulatory mechanisms of protein kinases.

F-Helix as a Structural Scaffold for Active Protein Kinase Assembly

Notes on 2008_PNAS paper revealing F-helix as a hub for regulatory and catalytic spine anchoring in protein kinases.

F-Helix as a Structural Scaffold for Active Protein Kinase Assembly

Notes on 2008_PNAS paper revealing F-helix as a hub for regulatory and catalytic spine anchoring in protein kinases.

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