Notes on 2014 ACS paper introducing DFGmodel, a computational approach to predict kinase inactive structures for type-II inhibitor discovery. Includes insights on DFG-flip and kinase conformational analysis.
Notes on 2014 ACS paper introducing DFGmodel, a computational approach to predict kinase inactive structures for type-II inhibitor discovery. Includes insights on DFG-flip and kinase conformational analysis.
Notes on 2024_ACS paper discussing the kinetic and structural principles of phosphorylation-driven protein switches and their biosensor applications.
Notes on 2024_ACS paper discussing the kinetic and structural principles of phosphorylation-driven protein switches and their biosensor applications.
